The purpose of this work is to monitor the seasonal activity of mealybug and the potential impacts of climatic conditions and plant ages on the insect population infesting maize plants at Esna district, Luxor Governorate, Egypt, during two seasons (2021 and 2022). Results showed that P. solenopsis attacked maize plants from the third week of June till crop harvest in all studied seasons, with three peaks of seasonal activity per season reported in the third/fourth week of July, the second week of August, and the first week of June. Likewise, there were three peaks in the percentages of infestation per season. The combined impacts of climatic conditions and plant ages have a substantial relationship with P. solenopsis population estimates, with an explained variance of 93.18 and 93.86 % in the two seasons, respectively. Furthermore, their effects explain differences in infestation percentages of 93.30 and 95.54% over the two seasons, respectively. Plant age was the most efficient factor in determining changes in the population densities of P. solenopsis over each season. However, the daily mean minimum temperature during the first season and the daily mean dew point for the second season were the major factors impacting the variations in infestation percentages. During both seasons, however, the daily mean maximum temperature was the least effective variable in population and infestation fluctuations. This research paves the way for monitoring, and early detection of mealybug on maize.